Adult Stem Cells Offer Hope for Back Pain Sufferers

December 2nd, 2006

Low back pain sufferers can look forward to a potential cure for their damaged disks and resulting pain. A research team at the University of Manchester, England, hopes that the new, patented treatment can be available within three years.

The therapy, developed by Dr. Stephen Richardson, would use injected adult stem cells taken from the patient’s own bone marrow. These mesenchymal stem cells (MSCs) have the ability to differentiate into many different cell types. The extracted stem cells are then embedded in a gel-like material where they are grown in a culture. The gel-like substance is similar to natural collagen already used to treat cartilage defects.
 
Dr. Richardson has been successful in turning MSCs into cells that make up the nucleus pulposus (NP) to provide cushioning between vertebrae. Because the stem cells are harvested from the patient’s own body, there is no chance of rejection by the immune system.

The British medical team reintroduces the cultured material into the damaged spinal disks through a tiny incision and using an arthroscope. The patient should be able to return home the same day after the procedure or the following day.

With treatments currently available to treat debilitating low back pain, success may be limited, and the cause of the pain is not completely addressed. This new procedure is expected to correct the root cause of the pain and give welcome relief from symptoms.

Pre-clinical trials will begin next year, after which full patient trials will take place. Although still in the early stages of development, the treatment appears very promising based on initial results.

Source:  BBC News

Entry Filed under: BACK PAIN,Chronic Pain,CHRONIC PAIN,MEDICAL DISCOVERIES